Archived David Kirn Scientific Publications – 2007

Targeting of interferon-beta to produce a specific, multi-mechanistic oncolytic vaccinia virus.

Kirn DH, Wang Y, Le Boeuf F, Bell J, Thorne SH. PLoS Med. 2007 Dec;4(12):e353....

Rational strain selection and engineering creates a broad-spectrum, systemically effective oncolytic poxvirus, JX-963.

Thorne SH, Hwang TH, O’Gorman WE, Bartlett DL, Sei S, Kanji F, Brown C, Werier J, Cho JH, Lee DE, Wang Y, Bell J, Kirn DH. J Clin Invest. 2007 Nov;117(11):3350-8....

Clinical trial results with oncolytic virotherapy: a century of promise, a decade of progress.

Liu TC, Galanis E, Kirn D. Nature Reviews Clin Oncol (prev NCPO). 2007 Feb;4(2):101-17....