Choroideremia Research Foundation (CRF)
In partnership with the Choroideremia Research Foundation, 4DMT seeks to develop a gene therapy product optimized for intravitreal administration to treat Choroideremia.
4DMT is conducting a Natural History Study for Choroideremia (CHM).
Natural History Studies track disease progression and are an essential first step in developing efficient clinical stages of testing in rare diseases. The purpose of this study is to evaluate disease progression as well as determine the feasibility of measuring endpoints for subsequent clinical trials in the hopes of providing medical benefit through gene therapy to all choroideremia patients and their families.
Two clinical sites are actively recruiting for the study:
This website will be updated as additional study sites open throughout the United States.
Eligibility requirements include but are not limited to: participants must be male, age 14 years or older, and have a CLIA Certified Genetic Diagnosis with visual acuity ≥ 20/200 or better.
Study participation requirements:
Attend Study Site Visits
Email Questions to CHM@4Dmoleculartherapeutics.com
For more information about Choroideremia, visit the Choroideremia Research Foundation (CRF) online. Additional clinical trial information including contact numbers may be found at clinicaltrials.gov, NCT 02994368.